I have always had a multi-pet household and have used a product called OdorMute successfully to treat the accidents that happen in the house. About 5 years ago, I adopted a rescue dog whose urine smell has defied my current treatment. I purchased Eco-88 based on the reviews on Amazon and tried it on one of her spots. AMAZING!!!!! The odor (which I had treated & cleaned numerous times) was 99% gone. In order to smell anything, I had to stick my nose into the fibers of the rug (and who's going to do that except me!). I am so thrilled, I am placing another order today. This will definitely become my go-to product from now on.

Update - 6/8/17: It's been over a month since I used Eco-88 on my carpet & the odor has not returned!!! I'm am truly impressed with this product.